Most specimens have been collected from shallow habitats, tide pools or 'brackish pools', at depths of 0-5 m, from sand and mangrove areas .
Dorsal spines (total): 7 - 8; Dorsal soft rays (total): 10 - 12; Anal spines: 1; Anal soft rays: 10 - 11. This large stocky Gnatholepis species (up to 64 mm SL) is distinguished by the following characters: cycloid scales on predorsal region, cheek and pectoral fin base; a distinct flap present at end of lower lip; 3 or more dark spots along first spine of first and second dorsal fins, followed by at least 3 rows of dark spots or short streaks; pectoral fin plain translucent to pale brownish; transverse black line crossing upper part of eye usually split in 2; anal fin plain dusky, often with one to several blackish rounded to oval spots posteriorly, or with dark streaks following membrane; D2 and A nearly always I,11; pectoral rays 15-17 (usually 16); lateral scales 25-29 (usually 27); predorsal scales 7-10 (usually 8-9) .: fusiform / normal; Cross section: compressed.
Behavioural data for Gnatholepis Knighti is currently being reviewed.
Marine; pelagic-neritic; depth range 0 - 5 m . Tropical Central Pacific: Known only from the Hawaiian island chain.
The following diseases are known to affect Gnatholepis Knighti.
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