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Parasitic 🔴 Fatal

Ceratomyxosis

🦠 Ceratomyxa shasta · Ceratomyxidae (Myxozoa)

📋 Overview

C. shasta destroys intestinal tissue causing fluid-filled swelling, peritonitis, and death. The polychaete worm Manayunkia speciosa serves as the alternate host. Hatchery fish from Columbia River populations vary widely in genetic resistance; some tributaries have extremely high parasite loads.

📊 Key Facts

Causative Agent
Ceratomyxa shasta
Agent Family
Ceratomyxidae (Myxozoa)
Peak Mortality
100%
Onset to Peak
weeks–months
Geographic Range
Pacific Northwest North America (Columbia River basin)
Transmission Routes
Via aquatic oligochaete Manayunkia speciosa; water-borne spores
Primary Host
Salmon and trout (Oncorhynchus spp.), Pacific salmonids
Treatment
✗ None
Vaccine
✗ None / Experimental
First Described
1948

🩺 Clinical Signs

Abdominal distension, yellow peritoneal fluid, liquefied gut contents, exophthalmia, lethargy, haemorrhagic intestines.

🔬 Symptoms

🔬
Abdominal distension
Abdominal Acute
🔬
Liquefied intestinal contents
Digestive Acute
🔬
Yellow peritoneal fluid
Abdominal Acute
🔬
Exophthalmia
Ophthalmic Subacute

🧪 Diagnosis

Histopathology of intestinal tissue, PCR for C. shasta, spore identification.

💊 Treatment

⚠️ No universally approved treatment is currently available. The information below covers supportive care and experimental approaches.
None effective. Fumagillin investigated but not licensed.

🛡️ Prevention

ℹ️ Prevention is the most effective strategy for managing this disease in aquaculture and aquarium settings.
Use resistant hatchery strains, bypass high-parasite river sections.